Integrated cardiac safety [electronic resource] : assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance / J. Rick Turner, Todd A. Durham.
Publication details: Hoboken, N.J. : John Wiley & Sons, c2009.Description: xxviii, 470 p. : illSubject(s): Genre/Form: DDC classification:- 616.1/23061 22
- RC677 .T87 2009eb
| Item type | Current library | Call number | URL | Status | Date due | Barcode | Item holds | |
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E-Book
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Strathmore University (Main Library) Online Resource | Link to resource | Not for loan |
Includes bibliographical references (p. 397-455) and index.
The importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety.
Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.
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