High-throughput screening methods in toxicity testing [electronic resource] / edited by Pablo Steinberg.

Contributor(s): Publication details: Hoboken, N.J. : Wiley, 2013.Description: xv, 552 p., [16] p. of plates : ill. (some col.)Subject(s): Genre/Form: DDC classification:
  • 615.1/9 23
LOC classification:
  • RS419.5 .H542 2013eb
Online resources:
Contents:
pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.
Summary: "High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"-- Provided by publisher.
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Item type Current library Call number URL Status Date due Barcode Item holds
E-Book E-Book Strathmore University (Main Library) Online Resource Link to resource Not for loan
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Includes bibliographical references and index.

pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.

"High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"-- Provided by publisher.

Electronic reproduction. Palo Alto, Calif. : ebrary, 2013. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.

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